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ADHD Medications For Adults Stimulants can help regulate levels of chemical messengers in the brain that regulate attention. They are first-line medications for treating ADHD. Although they are not in any way habit-forming, they can trigger side effects such as headaches and sleep problems. To decrease impulsivity or hyperactivity, your doctor may prescribe guanfacine under brand names Tenex or Intuniv (Catapres). These drugs are more effective than stimulants. Stimulants Stim