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Finding the Best Medication For ADHD It can take time to find an ADHD medication that works for you. It is essential to be honest with your physician about how ADHD affects you, so that they can prescribe the right medication for you. Stimulants, the most common treatment for ADHD, can cause negative side effects, such as mood and anxiety. Some sufferers also experience tics when taking stimulants. Methylphenidate Methylphenidate, which is the most popular medication for ADHD, is used by many people. It affects the chemical levels in