https://mdmsignaling.com/earli....er-estradiol-publici
While many inhibitors take on ATP, thus avoiding the catalytic task for the kinases right, a deep understanding of the systems of PI3K-dependent activation of its downstream effectors resulted in the development of extra strategies to stop the initiation with this signaling pathway. This analysis summarizes formerly published researches that led to the recognition of inositol polyphosphates as promising mother or father molecules to style unique inhibitors of PI3K-