https://www.selleckchem.com/pr....oducts/FK-506-(Tacro
Given GRP/GRPR pathway plays an important role in spinal itch transmission, we proposed that OT binds to the OTRs expressed on the GRP neurons, and activates GRP/GRPR pathway to trigger itch-scratching behaviors in mice. These findings provide novel evidence relevant for advancing understanding of OT-induced behavioral changes, which will be important for the development of OT-based drugs to treat a variety of psychiatric disorders.Gene therapy is an emerging and powerful therapeutic tool to deliver functional genetic materi
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