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The combination with phospholipids may solve the negative effects of NSAIDs and deliver derivatives with increased antitumor activity, whereas hybrids with terpenoids exhibit superior activity against their particular parent medications or actual mixtures. Consequently, the use of NSAIDs in cancer tumors therapy seems to be still an open chapter and requires deep and mindful evaluation. The literary works's data suggest the options of re-purposing anti-inflammatory medicines currently authorized for disease trea