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The study was designed to analyze the technical efficiency of input use among the sesame producer farmers' in Maykadra Kebelle, Kafta-Humera district, Tigrai, Ethiopia; identified factors that influence farmers' resource use efficiency. Primary and secondary data sources were used and random sampling method was applied to select 187 sample sesame producers. Primary data were collected using structured questionnaire interview. Tobit two-stage model was employed to estimate farmers' resource efficiency of sesame production. In the first sta