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Age was significantly, negatively correlated with DSS and ESS at the last follow-up. CONCLUSION Although LS and UES myotomy require a long inpatient rehabilitation and the risk of pneumonia after surgery is high, the outcome is favorable and the effects last for a long time.AIMS Acetaminophen (APAP) overdose leads to acute liver injury by inducing hepatic mito-chondrial oxidative stress and inflammation. However, the molecular mechanisms involved are still unclear. Farnesoid X receptor (FXR) serves as a therapeutic target for the treatme