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While regional brain alterations and functional connectivity in depressed suicidal patients have previously been reported, knowledge about gray matter (GM) structural networks is limited. The aim of this study was to explore the GM of depressed suicidal brains from the single-subject structural network level. This was a cross-sectional study, in which 50 healthy controls (HC, 31 ± 9 years), 50 major depressed patients without suicidality (NSD, 29 ± 10 years), and 50 major depressed patients with suicidality (SU, 29 ± 12 years) were enro