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In addition, we show the usefulness of the theoretical findings thought some simulation experiments. Finally, a real data set have been analyzed for illustrative purposes of our results.Disease-related gene prioritization is one of the most well-established pharmaceutical techniques used to identify genes that are important to a biological process relevant to a disease. In identifying these essential genes, the network diffusion (ND) approach is a widely used technique applied in gene prioritization. However, there is still a large numb