https://www.selleckchem.com/pr....oducts/cloperastine-
Lipolysis is closely associated with obesity and insulin resistance. Berberine (BBR), a natural alkaloid derived from Coptis chinensis, has been shown to regulate lipolysis and improve insulin resistance. However, the underlying mechanism remains unclear. The present results suggested that BBR stimulated lipolysis in porcine adipocytes in a dose‑ and time‑dependent manner, which was independent of the cAMP/protein kinase A pathway. Further experimental results indicated that BBR increased phosphorylation levels of AMP‑ac
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