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What Happens If ADHD is Left Untreated in Adults? Adults suffering from ADHD can experience a range of issues if the condition is not treated. These issues can affect relationships, work and mental health. Many times, people who suffer from untreated ADHD have low self-esteem and a pessimistic perspective on the world. This can cause them to feel like they are failing at work and at home. Inattention and lack of Focus It is normal to experience difficulty focusing from time to time especially afte