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ADHD and Sleep Medication People suffering from ADHD have difficulty sleeping. They are agitated when they finally get to sleep, and they are awake frequently throughout the night. Objective measures such as polysomnography and actigraphy indicate that children with ADHD have a longer sleep onset latency, lower sleep efficiency and shorter real sleep time than controls. Nevertheless, objective measures of sleeping improve with MPH treatment. 1. Restlessness medication to calm t