https://www.selleckchem.com/pr....oducts/necrostatin-1
Hyperosmolar agents frequently are used to decrease intracranial pressure but their effects on electrolyte and acid-base variables have not been prospectively investigated. Compare duration and magnitude of changes in electrolyte and acid-base variables after hyperosmolar treatment. Twenty-eight client-owned dogs with intracranial hypertension caused by various pathologies. Prospective, randomized, nonblinded, experimental cohort study. Fifteen dogs received a single dose (4 mL/kg) of 7.2% hypertonic saline (HTS), 13 dogs received