https://www.selleckchem.com/pr....oducts/eliglustat.ht
Together, our study revealed a novel mechanism underlying the arsenic-induced proteostatic stress in human cells.Conformational transitions in proteins facilitate precise physiological functions. Therefore, it is crucial to understand the mechanisms underlying these processes to modulate protein function. Yet, studying structural and dynamical properties of proteins are notoriously challenging due to the complexity of the underlying potential energy surfaces (PES). We have previously developed the perturbation-response scanning (PRS)
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