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cellular adhesion particles [CAMs]), surrounding cells and extracellular matrix (ECM). Repigmentation in vitiligo is dependent on the ECM remodeling and mobile migration, primarily related to the transcriptional activation of matrix metalloproteinases (MMPs).In the present study, we aimed to demonstrate the role of ETS-1 signaling into the legislation of MMPs and cameras. Consequently, we studied the phrase of ETS-1, MMPs (MMP-2, MMP-9); and Webcams including E-cadherin, ITGA-1 and IC