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How a VC Can Affect Your Heart A lot of people experience occasional PVCs with no problems. If they are frequent, PVCs may weaken your heart and increase your risk for heart failure. The rhythm of your heart is usually controlled by a group of fibers that are located in the upper right-hand part of your heart. This is known as the sinoatrial nerve, or SA. Electrical signals travel from there to the lower heart chambers, or ventricles. Causes PVCs occur when the electrical impulse that normally starts your heartbea
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