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Also, SG could up-regulate the expressions of PI3K, AKT, mTOR, 70S6K, BDNF, and Trkb. The blockade of mammalian target of rapamycin signaling blunted the antidepressant impact and reversed the up-regulation of BDNF expression due to SG. These findings proposed that SG treatment alleviated depressive-like signs via mTOR-mediated BDNF/Trkb signaling. © 2020 John Wiley Sons, Ltd.Tuberculosis is an illness widespread all over the globe with India adding to a
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