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cognitive symptoms in order to improve functional outcomes when treating patients with MDD. © 2020 Wang et al.Purpose Despite advances in characterizing the neurobiology of emotional disorders, there is still a significant lack of scientific understanding of the pathophysiological mechanisms governing major depressive disorder (MDD). This study attempted to elucidate the molecular circuitry of MDD and to identify more potential genes associated with the pathogenesis of the disease. Patients and Methods Microarray data from the GSE98793 da