https://www.selleckchem.com/pr....oducts/cdk2-inhibito
Interestingly, a deficiency of TCR IR (TcrbKO mice) led to a deterioration of liver fibrosis, coupled with activation of hepatic stellate cells (HSCs) induced by the upregulation of macrophage and γδ T cell distribution in fibrotic TcrbKO livers. Our findings reveal the landscape and dynamics of single immune cells in liver fibrosis, and clarify the protective role of TCR IR in response to chronic liver injury.We recently reported that the treatment with nanoparticles (NPs) loaded with tolerogenic cytokines suppressed the mani