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The stability of the rhodopsin molecule was proved to be determined by the degree of strength of its individual segments connected to each other. The AFM method is a highly accurate method that helps solve many fundamental and practical problems, particularly in ophthalmology. To identify the specifics of structural and functional changes in patients with toxic optical neuropathy caused by acute methanol poisoning. One female patient with toxic optic neuropathy (TON), 2 male patients with partial optic atrophy caused by methanol poison