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Atorvastatin significantly attenuated the activation of PKD and ERK5. Overall, this study demonstrated that atorvastatin could reverse vascular remodeling in SHRs. The PKD/ERK5 signaling pathway might be important for elucidating the beneficial pleiotropic effects of atorvastatin on vascular remodeling. This article is protected by copyright. All rights reserved.AIM Uncontrolled donation after cardiac death (uDCD) remains an underutilized source of kidney allografts in the United States. The objective of this study was to estimate the i