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ADHD Medications - Stimulant Or Non Stimulant? For many stimulant medication is the first choice for treating ADHD. Some suffer from negative side effects or they do not work for everyone. Some doctors prescribe stimulants in addition to non-stimulant ADHD medications. These include medicines that treat high blood-pressure like clonidine or Guanfacine (Tenex). They also include other medications that act to promote wakefulness. Benefits Stimulants are the