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The pks + E. coli metabolite colibactin caused a unique mutational signature in intestinal organoids. ©2020 American Association for Cancer Research.A new method called MicroMapping can identify nanoscale protein-protein interactions on live cells. ©2020 American Association for Cancer Research.A chemotherapy-induced shift to ICOSL+ B cells in breast tumors correlated with better survival. ©2020 American Association for Cancer Research.A large international study found that the composition of the intestinal microbiome can predict clinical