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injections may be indicated if secondary MNV develops. To describe intraocular clouding of silicone oil in the absence of emulsification. Retrospective observational case series of patients who received silicone oil injections and developed silicone oil discoloration without emulsification after pars plana vitrectomy. Clinical examinations and physicochemical analyses were performed to find out the common cause for the opaque oil. Thirteen patients developed silicone oil discoloration after pars plana vitrectomy. It could be traced down