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te, 13 August 2015), and [a]www.kofam.ch[/a] (SNCTP000001521). ClinicalTrials.gov NCT02554487 , retrospectively registered on 16 September 2015 (actual study start date, 13 August 2015), and [a]www.kofam.ch[/a] (SNCTP000001521).Recently, efforts have been made toward the harmonization of transcriptomic data structures and workflows using the concept of data tidiness, to facilitate modularisation. We present tidybulk, a modular framework for bulk transcriptional analyses that introduces a tidy transcriptomic data structure paradigm and analysis gramma