https://azaindole1inhibitor.co....m/predictors-regardi
We reveal FAIM counteracts intracellular buildup of mutant SOD1 protein aggregates, that will be increased when you look at the lack of FAIM, as determined by pulse-shape analysis and filter pitfall assays. In a cell-free system, FAIM prevents aggregation of mutant SOD1, and additional disassembles and solubilizes set up mutant SOD1 protein aggregates, as determined by thioflavin T (ThT), filter trap, and sedimentation as