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TGF-β1 expression ended up being repressed whenever HIF-1α inhibitors were included (p = 0.001), and HIF-1α expression had been upregulated when exogenous TGF-β1 ended up being added (p = 0.033) in N1S1 cells. Conclusion HAE improved local TGF-β1 phrase in a rat hepatoma design. In vitro experiments declare that HAE-induced hypoxic anxiety may trigger the interdependent phrase of TGF-β1 and HIF-1α. Copyright © 2019 by S. Karger AG, Basel.Introduction Radiof