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We conclude that these ncRNAs are examples for the inherent regulatory roles for many of the observed ncRNAs in response to changing conditions such as host interaction or environmental adaption.The hydroamidocarbonylation of alkynes with amides allows for the synthesis of α,β-unsaturated imides with the advantage of 100% atomic economy. Herein, the bifunctional ligand (L1) containing a sulfonic acid group (-SO3 H) and phosphino-fragment enable the Pd catalyst to accomplish the hydroamidocarbonylation of alkynes with amides. It was foun