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ous system alterations related to central neuropathic pain in MS patients that lead to the disturbances in cortical communication. Copyright © 2020 Krupina, Churyukanov, Kukushkin and Yakhno.Glucocorticoids are used intra-operatively in cochlear implant surgeries to reduce the inflammatory reaction caused by insertion trauma and the foreign body response against the electrode carrier after cochlear implantation. To prevent higher systemic concentrations of glucocorticoids that might cause undesirable systemic side effects, the drug shou