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02). Serum levels of TNF-α and IL-10 were comparable at all studied time points (P.05). Maternal serum levels of CXCL10 are significantly lower in the earliest implantation phase in di-di twins compared to singleton conceptions. Given the known anti-angiogenic role of CXCL10, we hypothesize that lower CXCL10 levels in twin implantations allow an environment that is conducive for the greater vascularization required for the establishment of dual placentation in di-di twins. Maternal serum levels of CXCL10 are significantly lower in t