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le prospective cohort studies are necessary to verify these associations in a methodologically more robust way.ObjectiveThe aim of the present study was to evaluate maintenance of the original anatomy of the root canal diameters instrumented with the Mtwo rotary instruments and BioRace file systems. Material and methodAcrylic resin blocks with 160 simulated root canals with an angle curvature 15°-30° were taken into consideration in the present comparative study. The 160 simulated root canals were divided into two groups, each of them