https://www.selleckchem.com/pr....oducts/pf-04929113.h
This sustainable all-organic nanocomposite is a promising candidate for biodegradable disposable commodities.A series of 11-substituted sampangine derivatives have been designed, synthesized, and tested for their ability to inhibit cholinesterase. Their chelating ability and selectivity for Cu2+ over other biologically relevant metal ions were demonstrated by isothermal titration calorimetry. Their blood-brain barrier permeability was also tested by parallel artificial membrane permeation assay. Among the synthesized derivatives, co
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