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ALK gene rearrangement expression was screened by immunohistochemistry (IHC) (D5F3 Clone). Good cases were then delivered for verification with Fluorescence in situ hybridization (FISH) method. RESULTS On immunohistochemistry, clients were distributed as after score 0 n=108, rating 1+ n=26, score 2+ n= 9, rating 3+ n= 9. ALK gene rearrangement had been detected in 6 out of 18 (2+ and 3+ rating) tested clients by FISH technique. The presence of ALK rearrangement was significa