https://www.selleckchem.com/pr....oducts/MGCD0103(Moce
0001). All the patients carrying the mutant allele had an early age of onset (p = 0.0001), higher incidence of bilateral disease (p = 0.002), positive family history (p = 0.03), higher Suzuki angiographic stage (≥3) (p0.0006) and recurrent neurological events (ischemic strokes and TIAs) (p = 0.009). The homozygous rs112735431(p.R4810K) variant in RNF 213 variant not only predicts the risk for MMD but can also predict the phenotypic variants. The homozygous rs112735431(p.R4810K) variant in RNF 213 variant n
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