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Particularly, CCND1, a vital regulator for G1/S transition, was dramatically reduced aided by the depletion of METTL7B, resulting in G0/G1 arrest, showing that METTL7B is crucial for mobile pattern development. Taken collectively, our findings implicate that METTL7B is vital for NSCLC development and progression. METTL7B might act as a potential therapeutic target for NSCLC. Copyright © 2020 Liu, Li, Zhong, Yin, Zhou, Li, sunlight, Xu, Li, We