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In this study, a label-free electrochemical biosensor had been designed to quantify the vascular endothelial development element A (165) (VEGF-A(165)) antigen, making use of decreased graphene oxide-gold nanoparticle for early detection of breast cancer. The conductivity of silver nanoparticle along with its biocompatibility offer an enhanced area, suited to anti-VEGF antibody immobilization. 11-mercaptoundecanoic ac