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Results The distribution of liver density was similar and the prevalence of severe steatosis (density less then 40 HU) was not different (4.7% vs 5.2%, p=0.7) between COPD and controls. In patients with COPD, the lowest liver density quartile was associated, after age and sex adjustment, with coronary artery disease (ORa=1.59, 95% CI 1.12 to 2.24) and stroke (ORa=2.20, 95% CI 1.07 to 4.5, in comparison with the highest liver density quartile. Conclusion The present data indicate that a low liver density emerged as a predictor of cardio