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There was, moreover, convincing proof from very early studies in Asia concerning the efficacy of CQ and HCQ in the anti-COVID-19 process. Since then, study and research reports have been massive to see these medications' efficacy and security in dealing with the viral infection. In the present review, we construct a synopsis associated with main properties and current data in regards to the metabolic process of CQ/HCQ, that have been the basis of assessing