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5 bar of applied pressure) by filtration of brackish feed streams. The optimized membranes achieve a ∼40 % improvement, in water permeance of ∼2.76±0.5 L m-2 h-1 bar-1 and high 99.5 % NaCl rejection with respect to the reference TFC membrane and a similar water permeance compared to one of the best commercial BW30 membranes (3.0 L m-2 h-1 bar-1 and 99.5 % NaCl rejection).Guanine-rich sequences are known to fold into G-quadruplex (G4) arrangements, which are present in oncogenes and in the telomeric regions of chromosomes. In partic