https://assayway.com/index.php..../temporal-developmen
Here, we show that T3-induced increase in energy expenditure needs thyroid hormones receptor alpha 1 (TRα1 ) in skeletal muscle mass, but that T3-mediated level in body temperature is attained in the lack of muscle-TRα1 . In slow-twitch soleus muscle mass, loss-of-function of TRα1 (TRαHSACre ) alters the fiber-type composition toward a more oxidative phenotype. The alteration in fiber-type composition, nonetheless, doe