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Medication For ADHD - What Are the Side Effects? Many people who suffer from ADHD experience a reduction in symptoms when they take medication. But every person reacts differently to different medications, and adverse reactions can be problematic. Methylphenidate is a stimulant. It is a stimulant that increases levels of a chemical within the brain that helps control the attention span and behavior. Stimulant medication Stimulant medications enhance concentration and attention in 70% to 80perce