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ADHD Medication - Ritalin (Methylphenidate) Ritalin (methylphenidate) increases two brain chemicals that control the ability to move and focus. It is among the most frequently prescribed medications for children with ADHD. It helps adults to focus better and be less aggressive. Some people take Ritalin with other ADHD treatments, like behavioral therapy. Certain medications may interfere with the medication. For instance, one shouldn't take it in conjunction with monoamine oxidase inhibitors such as isocarboxazid or rasagiline, linezolid, phenelzine or tranylcypr