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There was a significant difference in MD and FA (P=0.03, 0.001 respectively) of BM in GD with homozygous L444P mutation (n=9) and other mutations (n=14). Chiotriptase, HB and platelet count of patients was correlated with MD (r=-0.36, 0.42, -0.41) and FA (r=-0.47, -0.37, -0.46) respectively. DTI of vertebral BM can help in diagnosis and monitoring patients with GD after therapy and correlated with genotyping, and hematological biomarkers of GD. DTI of vertebral BM can help in diagnosis and monitoring patients with GD after therapy and c