https://cptsignal.com/index.ph....p/determination-of-t
The H137A replacement eliminates the catalytically obligatory general acid, thereby enabling crystallographic separation of oxyanionic tetrahedral intermediates. Finally, the acetate complex with the wild-type chemical signifies a product complex after dissociation of this polyamine coproduct. Taken together, these frameworks offer snapshots associated with reaction coordinate of acetylpolyamine hydrolysis and tend to be consistent with a mechanism by
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