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In response to dissolved oxygen fluctuation, metabolic profiles of two abalones changed in distinct ways both in the hypoxia group or the reoxygenation group. The conversion of carbohydrate metabolism and amino acid metabolism indicated that hypoxia prompts abalone to change the way of energy metabolism, which may also reflect the difference in the energy utilization of DD and DF abalones. In addition, 3 metabolites (L-glutamate, 2-hydroxy-butanoic acid, and 2-methyl-3-hydroxybutyric acid) as potential biomarkers for hypoxia and reoxyge
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