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The role of the circadian clock in regulating blood/breath alcohol levels after consuming alcohol is uncertain. Our goal was to evaluate the degree to which the circadian system regulates breath alcohol concentration (BrAC) pharmacokinetic parameters. Twenty healthy adults aged 21-30 y took part in a 4-d laboratory study. A 40-h constant routine procedure was used to assess circadian rhythms. Every 4h, participants were given a fixed oral dose of alcohol with breathalyzer measurements taken every 5min to construct BrAC curves. Sinusoid