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The purpose of this commentary is to identify the advantages and disadvantages of each questionnaire by critically analysing psychometric properties, identifying which OA domains are present, and evaluating additional features that are important to a questionnaire. BACKGROUND Vaccination against influenza is recommended for patients with common variable immunodeficiency (CVID), although humoral immune responses in these patients are impaired and the evidence of effective T-cell responses in CVID is not well established. OBJECTIVE To dete