https://www.selleckchem.com/pr....oducts/17-AAG(Geldan
Abnormal white matter signal with failure to display normal gray-white matter contrast persisted into adulthood. Cerebellar arbor vitae was not visible at any time point. Clinical signs, MRI findings, and pathological examinations were indicative of a hypomyelinating leukodystrophy. All parents of the affected litters shared a common ancestor and relatedness of the puppies suggested an autosomal recessive mode of inheritance. We describe a novel hypomyelinating leukodystrophy in German Shepherd dogs with a suspected inherit