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72%, which is more accurate by 47% than the Elman algorithm. For efficiency characteristic map representation, the RMSE of the extrapolation performance at higher and lower speed operating area by the proposed method is 2.85% and 1.22%, respectively. And the total RMSE by the proposed method is 1.81%, which is more accurate by 35% than the BP algorithm. Moreover, the proposed method has better real-time performance compared with the other three neural network algorithms. © 2020 The Authors.The interactions of novel anti-cancer therapeu