https://www.selleckchem.com/pr....oducts/Rapamycin.htm
Transcatheter closure of patent foramen ovale (PFO) in patients with cryptogenic stroke reduces the rate of recurrent events. Although presence of thrombophilia increases the risk for paradoxical emboli through a PFO, such patients were excluded from large randomized trials. We compared the safety and efficacy of percutaneous PFO closure in patients with and without a hypercoagulable state. Data from 800 consecutive patients undergoing percutaneous PFO closure in our medical center were analyzed. All patients were independently evalua